| Peer-Reviewed

Immunoglobulin a in Chronic Periodontitis Patients

Received: 11 February 2015     Accepted: 13 February 2015     Published: 2 March 2015
Views:       Downloads:
Abstract

Fourty-nine chronic periodontitis patients were diagnosed by dentist .Of which 27 were with generalized chronic periodontitis and 22 were with localized chronic periodontitis. The disease was prevalent among the age group range from 20 to 44 years old. Ten apparently healthy normal subjects were elected as control .Sera , saliva, salivary proteins were made for detection of IgA levels using radial immunodiffusion in gel containing low and high levels of anti-IgA ready made makes. Periodontitis patients sera have shown that, IgA concentration means reachs two to three folds higherthan that of controls.The IgA herd plot among the patients was of skewd distribution type. Young patients serum IgA were showing higher than that of senescence periodontitis patients and higher than that of normal control subjects .Male patients serum IgA were of higher concentration means than that of female patients. Apparently senescence decreases serum IgA concentration means as compared to young patients and controls.

Published in American Journal of Biomedical and Life Sciences (Volume 3, Issue 4-1)

This article belongs to the Special Issue Advances in Oral Immunity

DOI 10.11648/j.ajbls.s.2015030401.11
Page(s) 1-3
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Chronic, Periodotitis, Serum, Saliva, Proteins, Plot, Herd

References
[1] Doan T, Melvold R, Viselli S, Waltenbaugh C,2008, Immunology, Linppicotts Illustrated Review, Wolter Kluwer-Health ,Philadelphia.
[2] Paul W 2003, Fundamental Immunology 5th ed. Lippincott Williams and Wilkins,Philadelphia.
[3] Steward M W 1984, Antibodies; Their Structure And Functions ,Chapman and Hall Ltd, London
[4] Abbas AK , Litchman AH , Pober J S, 2000, Cellular And Molecular Immunology, 4th ed. W B Saunders, U.S.A.
[5] Bucci L 2009, Inflammoaging,In Fluop T, Franceschi C, Hirokawa K, Pawelec G (eds) .Handbook on immunosenescence Springer ,Netherland.
[6] Goto M 2008, Inflammoaging:A deriving force for human ageing based on evolutionary antagonistic pleotopytheory , Biosci .Trends ,2(6):218-230.
[7] Strober W ,Fuss I J ,2001, Mucosal immune System , In, Parslow TG , Stites DP , Terr AI, ImbodenJB (eds),Medical Immunology 10thed,Lange Medical Books,New York.
[8] Nikolopoulou-Papconstantinou AA , Johannessen AC, Kristoffsen T, 1987, Deposits of immunoglobulins, complements and immune complexes in inflamed human gingiva, Acta.Odontol. Scand., 45(3):187-199.
[9] Mills MP, 2013, Immunological and Inflammatory aspects of periodontal disease ,Dental Care continuing education ,course no.1.
[10] Armitage GC 1999, Development of a classification of periodontal diseases , Anns .Periodontol., 4:1-6.
[11] Stevens CD 2010, Clinical Immunology And Serology :A Laboratory perspective, 3rded.F.A. Davis Company, Philadelphia.
[12] Salimeterics 2013,Saliva collection and handling, 3rded., Saliva B Co.A Salimeterics LLC Co.
[13] Shnawa IMS , AlSadi MAK 2001, Gut mucosal immunoglobulin, separation ,partial characterization and utility as infection probe, Irq.J.Microbiol.13(3):
[14] Jonston A, Thorpe R 1982, Immunochemistry In Practice, Blackwell Scientific Publications , London.
[15] Mancini G , Corbonara A O , Heremans JF 1965, Immunochemical quantitation of antigens by single radial diffusion, Immunochem., 2:237
[16] Steel RCD , Torrie JH ,Dickey DA 1997, Priciples And Procedures of Statistics: A biomedical Approach,3rded., McGraw-Hill, New York.
[17] Dumitrescu AL, Kawamura M 2010, Etiology of periodontal disease ,In, Dumitrescu AL ,Etiology and Pathogenesis of Periodotal Diseases ,Springer ,Berlin, Heidlberg.
[18] DumitrescuAL, Tanaka M 2010, Particular Aspects of Periodontal Disease Pathogenicity, In , Dumittrescu AL ,Etiology and Pathogenesis Of Periodontal Disease , Spriger ,Berlin ,Heidelberg
[19] Walsh LJ 2008, Clincal aspects of salivary biology for detal clinician .J. Min .Inter . Dntist. ,1(1):7-24.
[20] Boackl RJ 1991, Interaction of salivary secretion with human complement system .A model for study host defence system on inflamed surfaces., Crit.Rev.Oral.Biol.Med., 2(2):355-367.
[21] Olayanju QA, Rahmon SK, Joseph IO, Arinola, 2012, Salivary immunoglobulin classes in Nigerian patients with periodontitis, J.Contm.Dent.Pract., 13(2):163-166.
Cite This Article
  • APA Style

    Ibrahim M. S. Shnawa. (2015). Immunoglobulin a in Chronic Periodontitis Patients. American Journal of Biomedical and Life Sciences, 3(4-1), 1-3. https://doi.org/10.11648/j.ajbls.s.2015030401.11

    Copy | Download

    ACS Style

    Ibrahim M. S. Shnawa. Immunoglobulin a in Chronic Periodontitis Patients. Am. J. Biomed. Life Sci. 2015, 3(4-1), 1-3. doi: 10.11648/j.ajbls.s.2015030401.11

    Copy | Download

    AMA Style

    Ibrahim M. S. Shnawa. Immunoglobulin a in Chronic Periodontitis Patients. Am J Biomed Life Sci. 2015;3(4-1):1-3. doi: 10.11648/j.ajbls.s.2015030401.11

    Copy | Download

  • @article{10.11648/j.ajbls.s.2015030401.11,
      author = {Ibrahim M. S. Shnawa},
      title = {Immunoglobulin a in Chronic Periodontitis Patients},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {3},
      number = {4-1},
      pages = {1-3},
      doi = {10.11648/j.ajbls.s.2015030401.11},
      url = {https://doi.org/10.11648/j.ajbls.s.2015030401.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.s.2015030401.11},
      abstract = {Fourty-nine chronic periodontitis patients were diagnosed by dentist .Of which 27 were with generalized chronic periodontitis and 22 were with localized chronic periodontitis. The disease was prevalent among the age group range from 20 to 44 years old. Ten apparently healthy normal subjects were elected as control .Sera , saliva, salivary proteins were made for detection of IgA levels using radial immunodiffusion in gel containing low and high levels of anti-IgA ready made makes. Periodontitis patients sera have shown that, IgA concentration means reachs two to three folds higherthan that of controls.The IgA herd plot among the patients was of skewd distribution type. Young patients serum IgA were showing higher than that of senescence periodontitis patients and higher than that of normal control subjects .Male patients serum IgA were of higher concentration means than that of female patients. Apparently senescence decreases serum IgA concentration means as compared to young patients and controls.},
     year = {2015}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Immunoglobulin a in Chronic Periodontitis Patients
    AU  - Ibrahim M. S. Shnawa
    Y1  - 2015/03/02
    PY  - 2015
    N1  - https://doi.org/10.11648/j.ajbls.s.2015030401.11
    DO  - 10.11648/j.ajbls.s.2015030401.11
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 1
    EP  - 3
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.s.2015030401.11
    AB  - Fourty-nine chronic periodontitis patients were diagnosed by dentist .Of which 27 were with generalized chronic periodontitis and 22 were with localized chronic periodontitis. The disease was prevalent among the age group range from 20 to 44 years old. Ten apparently healthy normal subjects were elected as control .Sera , saliva, salivary proteins were made for detection of IgA levels using radial immunodiffusion in gel containing low and high levels of anti-IgA ready made makes. Periodontitis patients sera have shown that, IgA concentration means reachs two to three folds higherthan that of controls.The IgA herd plot among the patients was of skewd distribution type. Young patients serum IgA were showing higher than that of senescence periodontitis patients and higher than that of normal control subjects .Male patients serum IgA were of higher concentration means than that of female patients. Apparently senescence decreases serum IgA concentration means as compared to young patients and controls.
    VL  - 3
    IS  - 4-1
    ER  - 

    Copy | Download

Author Information
  • College of Biotechnology, University of Kasim, Kasim, Babylon Governerate/IRAQ

  • Sections